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Obesity

Hospital-based Medicine

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Adolescent Medicine
Session Type: Hot Topic Symposia

Improving Access and Outcomes in Pediatric Renal Transplant Recipients

Sunday, May 2, 2021
1:00 PM - 3:00 PM US CT
CE: 2

Live Session
Course Number: 2415-SS-L
Format Type: Live
Target Audience: pediatric nephrologists, transplant physiciancs, scientists

Session Description:

    Chair(s)

  • Amy Bobrowski, MD MS

    Pediatric Nephrologist
    Pediatric Nephrology
    Cleveland Clinic Children's
    Cleveland, Ohio, United States

  • SM

    Scott McEwen, MD, PhD

    Assistant Professor
    Pediatric Nephrology
    University of Minnesota Twin Cities
    Minneapolis, Minnesota, United States

Learning Objectives:

  • 1. To describe the current data relating degree of HLA match to outcomes in pediatric kidney transplant, and to present and evaluate possible strategies for addressing this challenging issue. 2. To identify current biomarker panels available for monitoring of acute kidney dysfunction in transplantation. 3. To describe the prevalence and pathophysiology of CVD risk factors in pediatric patients with a history of CKD/kidney transplant, and to present available evidence on the benefit of strategies to address those that are modifiable. 4. To discuss existing and possible multidisciplinary strategies and programs that promote and teach healthy lifestyle choices (dietary, physical activity), and eventual self-sufficiency—both in navigating and managing healthcare, and in managing life. 5. To discuss methods to increase access to pediatric transplantation. CDC high risk donors, ABOi donors, desensitization, donor exchange programs, organ allocation policy and more.
The goal of this session is to address specific issues that contribute to shortened lifespan, even after successful pediatric kidney transplantation. The leading cause of late mortality is premature cardiovascular disease, and this risk of death is much greater after graft failure and return to dialysis. Therefore, strategies to improve immunologic outcomes and prolong the life of a child’s first graft are paramount, and will be addressed in the first 2 talks. The second 2 talks will focus reducing mortality in our patients who are already successfully transplanted per our current protocols. First we will discuss the current data on CVD outcomes in this population, and the relative roles of both modifiable and non-modifiable risk factors. The final talk will address multidisciplinary ideas for practical, programmatic ways to teach and encourage healthy lifestyle choices, and to empower transplant recipients toward self-sufficiency and self-care as they mature.

Presentations:

  • 1:00 PM - 1:22 PM US CT
    H. William Schnaper, MD lecture: Increasing the donor pool for pediatric kidney transplant recipients

    Presenter: Stephen Marks, MD, MSc, MRCP (UK), DCH, FRCPCH – University College London Great Ormond Street Institute of Child Health

  • 1:22 PM - 1:44 PM US CT
    Implications of degree of HLA Match/Strategies to Improve HLA matching in Pediatric Kidney Transplantation

    Presenter: Rachel Engen, MD, MS – Northwestern University Feinberg School of Medicine

  • 1:44 PM - 2:06 PM US CT
    Biomarkers of acute rejection, under and over- immunosuppression

    Presenter: Tom Blydt-Hansen, MDCM, FRCPC – University of British Columbia

  • 2:06 PM - 2:28 PM US CT
    Cardiovascular Disease Risk Factors and lifestyle modification strategies after Pediatric Kidney Transplantation: What are We Dealing With, and What Can We Target?

    Presenter: Elaine Ku, MD MAS – UCSF

  • 2:28 PM - 3:00 PM US CT
    Q&A

    Presenter: Belinda Thomas