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Discussion + Q&A ViewAttendees 208

Live Q&A for this session: Sunday, May 2 11:30 am to 12:00 pm CST. Please watch the presentations in advance of this time.

Neonatology

Neurology

Session Type: Hot Topic Symposia

The Neurological Implications of Abnormal Glycemia in Neonatal Encephalopathy and Prematurity

Sunday, May 2, 2021

9:00 AM - 12:00 PM US CT

CE: 2

Course Number: 2220-SS-QA
Format Type: On-Demand with Live Q&A
Target Audience: Scientists and clinicians at all career stages interested in neonatal brain injury and improving developmental outcomes.

Session Description:

Chair(s)

Emily Tam, MDCM, MAS, FFRCPC

Associate Professor
Pediatrics
Hospital for Sick Children
Toronto, Ontario, Canada
Sudeepta Basu, MBBS, MS

Assisstant Professor
Pediatrics-Neonatology
Children's National Hospital
Children's National Hospital & The George Washington University
Washington, District of Columbia, United States
Elana Pinchefsky, MDCM, MSc, FRCPC

Neurologist
Centre Hospitalier Universitaire Sainte-Justine
Montreal, Quebec, Canada

Learning Objectives:

- Understand normal glucose metabolism during postnatal transition - Identify special circumstances leading to disturbed glycemic homeostasis in newborns with neonatal encephalopathy and prematurity - Understand the impact of hypoglycemia in the well newborn - Identify the distinct relationships of hypoglycemia and hyperglycemia with brain injury and adverse outcomes after neonatal encephalopathy - Identify the impact of abnormal glycemia on brain injury and adverse outcomes after preterm birth

Hypoglycemia and hyperglycemia have important implications to the developing brain, especially in newborns with neonatal encephalopathy or born preterm. This Symposium will discuss neonatal glucose homeostasis and brain metabolism with special emphasis on the newborns with high risk of neurologic injury. We will discuss the lessons learned from hypoglycemia in asymptomatic infants which can guide management of other cohorts of at-risk newborns. We will review the emerging evidence for distinct neuroimaging and electrographic phenotypes of brain injury and adverse outcomes in relation with early glycemic status in newborns with hypoxic ischemic encephalopathy. We will also review the current understanding and management recommendations for disturbed glycemic status in preterm newborns with emphasis on neurodevelopmental outcomes.

Presentations:

9:00 AM - 9:15 AM US CT

Perturbation of neonatal glucose metabolism and homeostasis in neonatal encephalopathy and prematurity
Presenter: Jeffrey R. Kaiser, MD, MA – Hershey Penn State Children's Hospital
9:15 AM - 9:35 AM US CT

Lessons from asymptomatic neonatal hypoglycemia
Presenter: Jane Harding, MBChB, DPhil, FRACP – Liggins Institute, University of Auckland
9:35 AM - 9:55 AM US CT

Abnormal glycemia and neonatal encephalopathy: neuroimaging and neurophysiology
Presenter: Emily W.Y Tam, MDCM, MAS, FFRCPC – Hospital for Sick Children
9:55 AM - 10:15 AM US CT

Abnormal glycemia and neonatal encephalopathy: outcomes
Presenter: Sudeepta K. Basu, MBBS, MS – Children's National Hospital
10:15 AM - 10:30 AM US CT

Abnormal glycemia after preterm birth
Presenter: Elana Pinchefsky, MDCM, MSc, FRCPC – Centre Hospitalier Universitaire Sainte-Justine
10:30 AM - 11:30 AM US CT

Break
Presenter: Belinda Thomas
11:30 AM - 12:00 PM US CT

Click for Live Q&A: The Neurological Implications of Abnormal Glycemia in Neonatal Encephalopathy and Prematurity
Presenter: Belinda Thomas