Scholarly Sessions

Infectious Diseases

Hospital-based Medicine

Pharmacology

Health Services Research

Cross-Disciplinary Pathway

Clinical Research Pathway

Allergy, Immunology and Rheumatology

Tackling the Penicillin Allergy Label: A Multidisciplinary Perspective of Allergy De-labeling

Chair(s)

• 

  James Antoon, MD, PhD

  Assistant Professor
  Pediatrics
  Vanderbilt University School of Medicine
  Vanderbilt University School of Medicine
  Nashville, Tennessee, United States

Ten percent of the U.S. population is labeled penicillin (PCN) allergic. Recent studies have demonstrated that the majority of symptoms reported as an allergy by parents are often low-risk non-IgE mediated adverse reactions. The majority of these are cutaneous reactions that are frequently interpreted as PCN-induced but are often viral or viral-drug mediated and are not a contraindication for future PCN use. Studies have shown that the presence of a PCN allergy label results in the avoidance of the entire antibiotic class with subsequent use of broader spectrum, and more expensive suboptimal antibiotics. Appropriately de-labeling PCN allergy has been shown to improve patient safe care through antimicrobial stewardship and lowering health care costs. Recent studies have highlighted approaches for de-labeling children with PCN allergy, however rates of de-labeling remain low and a more systematic approach is needed. Furthermore, there is significant variation among institutions, clinical settings and individuals concerning which patients can be de-labeled, and how to de-label and in the different settings.

Presentations:

• 1:00 PM - 1:10 PM US CT

  Introduction to Allergy De-labeling
  

  Presenter: James W. Antoon, MD, PhD – Vanderbilt University School of Medicine
• 1:10 PM - 1:30 PM US CT

  Who Can be Safely De-labeled in Primary Care Clinic? Screen for Success
  

  Presenter: Allison Norton, MD – Vanderbilt University
• 1:30 PM - 1:50 PM US CT

  The Nuts & Bolts of Delabeling: Who to Challenge and How?
  

  Presenter: Amol Purandare, MD – Children's Mercy Hospital
• 1:50 PM - 2:10 PM US CT

  The Challenge of Oral Challenges: Barriers to Delabeling
  

  Presenter: David Vyles, DO, MS – Medical College of Wisconsin
• 2:10 PM - 2:30 PM US CT

  Where Do We Go From Here? Impact, Metrics and Future Directions
  

  Presenter: Jennifer Goldman, MD, MSCR – Children's Mercy Hospital
• 2:30 PM - 3:00 PM US CT

  Q&A
  

  Presenter: Belinda Thomas