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Discussion + Q&A ViewAttendees 54

Mental Health

Global Neonatal & Children's Health

Children with Chronic Conditions

Nephrology

Allergy, Immunology and Rheumatology
Session Type: Basic-Translational-Clinical Roundtable

Childhood-Onset Lupus: A Global and Multisystem Disease

Tuesday, May 4, 2021
4:30 PM - 7:00 PM US CT

On-Demand with Live Q&A
Course Number: 4800-SS-QA
Format Type: On-Demand with Live Q&A
Target Audience: Pediatricians, Subspecialists, Trainees

Session Description:

    Chair(s)

  • Laura Ballenger, MD, RhMSUS

    Pediatric Rheumatologist
    Rheumatology
    Nationwide Children's Hospital
    Columbus, Ohio, United States

  • Jay Mehta

    Associate Professor of Clinical Pediatrics
    University of Pennsylvania Perelman School of Medicine The Children's Hospital of Philadelphia
    The Children's Hospital of Philadelphia
    Philadelphia, Pennsylvania, United States

Learning Objectives:

  • 1. Understand the genetic architecture of cSLE including common variants, associations with subtypes like lupus nephritis, and monogenic forms of the disease. 2. Describe the current epidemiology of cSLE in global populations to highlight gaps in access to care and research. 3. Describe the prevalence, risk factors, impact, and treatment of psychiatric comorbidity in patients with cSLE. 4. Explain approaches to blood pressure and fluid management in the cSLE patient, including approach to hypertension, adverse effects from corticosteroids, and cardiovascular disease.
This session will highlight aspects of childhood-onset systemic lupus erythematosus (cSLE) beyond the clinical diagnosis and immunosuppressive treatment. The first presentation will discuss genetic associations in cSLE and implications for treatment of sub-phenotypes and monogenic forms of the disease. The second presentation will continue the discussion of the genetic landscape of cSLE from a global population perspective and include review of global disparities in access to care and gaps in research. The third presentation will address psychiatric comorbidity in patients with cSLE and strategies for mental health intervention. Lastly, the fourth presentation will review treatment of hypertension and edema from nephritis, sodium and fluid retention from steroids, BP control of extra-renal vasculitis, and cardiovascular disease in patients with cSLE.

Presentations:

  • 4:30 PM - 4:55 PM US CT
    Genetics of childhood-onset SLE

    Presenter: Linda T. Hiraki, MD, FRCPC, ScD – The Hospital for Sick Children

  • 4:55 PM - 5:15 PM US CT
    Global Disparities in childhood-onset SLE: Access to care and research

    Presenter: Laura B. Lewandowski, MD, MS – National Institute of Arthritis and Musculoskeletal and Skin Diseases

  • 5:15 PM - 5:35 PM US CT
    Addressing Mental Health in childhood-onset SLE

    Presenter: Andrea Knight, MD, MSCE – Hospital for Sick Children

  • 5:35 PM - 6:00 PM US CT
    Lupus nephritis: blood pressure, fluid management and cardiovascular risks

    Presenter: Scott E. Wenderfer, MD, PhD, FASN – Baylor College of Medicine

  • 6:00 PM - 6:30 PM US CT
    Break

    Presenter: Belinda Thomas

  • 6:30 PM - 7:00 PM US CT
    Click for Live Q&A: Childhood-Onset Lupus: A Global and Multisystem Disease

    Presenter: Belinda Thomas