Neonatology

Neurology

Management of Post-Hemorrhagic Ventricular Dilatation in the Preterm Infant

Chair(s)

• 

  Terrie Inder, MBChB, MD

  Chair, Department of Pediatric Newborn Medicine
  Brigham and Women's Hospital
  Boston, Massachusetts, United States
• 

  Mohamed El-Dib, MD

  Director of Neonatal Neurocritical Care
  Pediatric Newborn Medicine
  Brigham and Women's Hospital
  Harvard Medical School
  Boston, Massachusetts, United States

Progressive post-hemorrhagic ventricular dilatation (PHVD) affects more than half of extremely premature infants with severe intraventricular hemorrhage and contributes to their high risk for adverse motor and cognitive neurodevelopmental outcomes. Despite being investigated for many decades, there is no agreement among neonatologists, pediatric neurologists, and neurosurgeons as to the best management approach to PHVD. Very recently, the ELVIS study (Randomized Controlled Early versus Late Ventricular Intervention Study) demonstrated improved 2- year outcome in the early intervention group.

This hot topic symposium will be led by experts in the field who will elaborate on the following aspects:

- Pathophysiology and neuropathology of PHVD- Terrie Inder

- Intervention studies for PHVD- Linda de Vries

- Surgical interventions for PHVD- David Limbrick

- Future directions and other neuroprotectors- Praveen Ballabh

- Consensus approach for evaluating and managing PHVD- Mohamed El-Dib

This will be followed by panel Q&A allowing for audience interaction.

Presentations:

• 1:00 PM - 1:20 PM US CT

  Pathophysiology and neuropathology of Post-Hemorrhagic Ventricular Dilation
  

  Presenter: Terrie Inder, MBChB, MD – Brigham and Women's Hospital
• 1:20 PM - 1:40 PM US CT

  Intervention studies for Post-hemorrhagic Ventricular Dilatation
  

  Presenter: Linda de Vries, MD, PhD – UMCU
• 1:40 PM - 1:55 PM US CT

  Surgical interventions for Post-hemorrhagic Ventricular Dilatation
  

  Presenter: David Limbrick, MD, PhD – St. Louis Children's Hospital
• 1:55 PM - 2:15 PM US CT

  Future directions and other neuroprotectors in the preterm infant
  

  Presenter: PRAVEEN BALLABH, MD – Children Hospital at Montefiore
• 2:15 PM - 2:30 PM US CT

  Consensus approach for evaluating and managing Post-hemorrhagic Ventricular Dilatation
  

  Presenter: Mohamed El-Dib, MD – Brigham and Women's Hospital
• 2:30 PM - 3:00 PM US CT

  Q&A
  

  Presenter: Belinda Thomas